POS0208-HPR PATIENT CHARACTERISTICS AND DIAGNOSIS SETTING OF PATIENTS WITH PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE IN GERMANY: A RETROSPECTIVE HEALTH CLAIMS DATA ANALYSIS

Background Osteoarthritis of the knee (knee OA) is most prevalent form OA in Germany as well globally [1] , frequently leading to pain and functional limitations. Several risk factors have been identified for osteoarthritis, which can be divided into those at person level (age, sex, obesity, genetic predisposition, physical activity diet) joint (injuries, malposition overstress) [2] . Patients with OA-like symptoms may present a number different medical specialties therefore arrive diagnosis Knee via routes. The population highly co-morbid one. In addition patients often hypertension diabetes [3] Objectives study focuses on Germany, aiming determine prevalence years 2015-2020, setting comorbidities between 2015 2020. Methods A non-interventional, retrospective health claims data analysis, performed anonymized, age- sex-representative sample Institute Applied Health Research Berlin GmbH (InGef) database. database used this includes approximately 4.8 million persons from approx. 60 statutory insurances (SHI) representative German [6]. ≥18 age were analyzed cross-sectionally each year 2015-2020. Using ICD-10-GM ATC codes. Results ranged 7.1% 7.6% 2019, dropping 7.4% incidence showed less linear pattern ranging 1.71% 2016, 1.67% 2017, 1.61% 2018, 1.67 2019 1.46% Females aged ≥66 had both higher proportion compared males younger persons. First was made an outpatient (93.4%) by orthopedics (49.88%), general practitioners (28.17%) specialists (Internist; 9.34%). Most co-morbidities all observed primary >70%. Other metabolic disorders like lipoprotein metabolism (around 50%), overweight obesity (28-30%), type 2 mellitus 27%) are among 10 common ones. musculoskeletal frequent (dorsalgia 54%; spondylosis 33-34%). percentage major depressive high (23%). Conclusion slowly increasing 2015-2019 possibly due growing population, however slightly decreasing Diagnosis mainly done orthopedist or practitioner. certain co-morbidities, cardiovascular system (hypertension highest percentage), but also condition (Disorders other lipidemias, diabetes) demonstrates that known increasing. Treating challenging managing drug-drug interactions given considerable treatments could receiving. This these physicians do not always know about non-prescription co-medications. Models care include tolerable, non-systemic treatments, enabling patient physiotherapy management aspects their actively key advancement. References [1]Woolf AD, Pfleger B (2003) Burden conditions. Bull World Organ 81(9):646-656 [2]Fuchs J, Kuhnert R, Scheidt-Nave C. (2017) 12-month osteoarthritis Germany. Journal Monitoring · 2(3) DOI 10.17886/RKI-GBE-2017-066 Robert Koch Institute, [3]Ludwig M., Enders D., Basedow J. et al. (2022) Sampling strategy, characteristics representativeness InGef research Public 206: 57-62 Acknowledgements: NIL. Disclosure Interests Dominik Beier Consultant of: Consultancy Grunenthal GmbH, Dennis Haeckl Stefan Ivanavicius Employee Jörg Jerosch Hiltrud Liedgens GmbH.